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Strain
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Fold change relative to AppA (PAOX1)
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Fold change relative to AppA (PHpFMD)
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Fold change relative to AppA-PDI (PHpFMD-HpMOX)
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AppA (PHpFMD)
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1.53 ± 0.01*
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–
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–
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AppA-HAC1 (PHpFMD-HpMOX)
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2.08 ± 0.07*
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1.36 ± 0.05**
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–
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AppA-HAC1 (PAOX1-CAT1)
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1.31 ± 0.09*
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0.86 ± 0.06**
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–
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AppA-HAC1 (PDAS1/2)
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0.54 ± 0.03*
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0.35 ± 0.02**
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–
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AppA-PDI (PHpFMD-HpMOX)
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2.14 ± 0.03*
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1.40 ± 0.02**
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–
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AppA-PDI (PAOX1-CAT1)
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1.71 ± 0.07*
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1.12 ± 0.05**
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0.80 ± 0.03***
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AppA-PDI (PDAS1/2)
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1.53 ± 0.50*
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1.00 ± 0.13
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0.71 ± 0.09***
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AppA-MPDI (PHpFMD-HpMOX)
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0.68 ± 0.16*
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0.44 ± 0.10**
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–
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AppA-EUG1 (PHpFMD-HpMOX)
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1.37 ± 0.02*
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0.90 ± 0.01**
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–
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AppA-SEC1 (PHpFMD-HpMOX)
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1.54 ± 0.04*
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1.01 ± 0.02
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–
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AppA-SLY1 (PHpFMD-HpMOX)
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1.63 ± 0.01*
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1.06 ± 0.01
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–
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AppA-ERV2 (PHpFMD-HpMOX)
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2.38 ± 0.03*
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1.56 ± 0.02**
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1.11 ± 0.01***
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AppA-ERO1 (PHpFMD-HpMOX)
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0.79 ± 0.11*
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0.52 ± 0.07**
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0.38 ± 0.05***
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AppA-PDI-ERO1 (PGAP)
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2.59 ± 0.12*
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1.70 ± 0.08**
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1.21 ± 0.06***
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AppA-PDI-ERO1 (PCAT1)
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2.33 ± 0.24*
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1.52 ± 0.16**
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1.09 ± 0.11
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AppA-PDI-ERV2 (PGAP)
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2.90 ± 0.08*
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1.90 ± 0.05**
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1.35 ± 0.04***
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AppA-PDI-ERV2 (PCAT1)
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2.42 ± 0.12*
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1.59 ± 0.08**
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1.13 ± 0.05
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AppA-PDI-GPX1 (PGAP)
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1.71 ± 0.01*
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1.12 ± 0.01
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0.80 ± 0.01***
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AppA-PDI-GPX1 (PCAT1)
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2.8 ± 0.31*
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1.83 ± 0.20**
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1.30 ± 0.14***
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AppA-PDI-HAC1 (PCAT1)
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2.26 ± 0.35*
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1.48 ± 0.16**
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1.06 ± 0.16
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AppA-HAC1-PDI (PGAP)
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1.72 ± 0.23*
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1.13 ± 0.15
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0.80 ± 0.11***
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AppA-PDI-KAR2 (PGAP)
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2.01 ± 0.01*
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1.32 ± 0.01**
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0.94 ± 0.02
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- aAll strains have a single copy of the integrated cassette (CNV = 1) as determined by ddPCR
- *Significantly different from AppA (PAOX1) (p value ˂ 0.05)
- **Significantly different from AppA (PFMD) (p value ˂ 0.05)
- ***Significantly different from AppA-PDI (PHpFMD-HpMOX) (p value ˂ 0.05)
